Icy conditions on Yellowstone River Bridge resulted in a 30 car pile-up shortly before noon on Saturday, the Montana Highway Patrol said.
No deaths have been reported but two individuals are critically injured.
Part of I-90 was closed as it took over two hours for officials to tow all the wrecked vehicles away from the scene.
It was around 30 degrees in Billings when the crash took place.
The Montana Department of Transportation reported entire blockage of the eastbound and westbound lanes of traffic at the time of the incident.